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Generally speaking, dose selection for an elderly affected person really should be cautious, usually starting off on the low end of your dosing selection, reflecting the bigger frequency of decreased hepatic, renal or cardiac function, and of concomitant illness or other drug therapy.

This product or service might consist of inactive elements, which often can trigger allergic reactions or other complications. Speak with your pharmacist For additional information.

To assist prevent withdrawal, your health practitioner might reduced your dose slowly but surely. Withdrawal is a lot more possible Should you have employed this medication for a very long time (more than a few weeks) or in large doses. Inform your health care provider or pharmacist straight away For those who have withdrawal.

g., All those with proof of amplified intracranial force or Mind tumors), Promethazine HCl and Codeine Phosphate Oral Remedy may well reduce respiratory drive, and the resultant CO2 retention can even further raise intracranial force. Also, opioids deliver adverse reactions that could obscure the scientific class of patients with head injuries.

The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients lower than 6 decades of age. Concomitant administration of promethazine merchandise with other respiratory depressants has an association with respiratory despair, and occasionally Dying, in pediatric patients. The Affiliation does not directly relate to individualized excess weight-dependent dosing, which could otherwise allow Secure administration.

This medication may perhaps interfere with specified lab exams (including urine pregnancy exams, pores and skin allergy exams), perhaps creating Bogus exam benefits. Make sure lab staff and your Medical doctors know you employ this drug.

Recommend patients to usually use an correct milliliter measuring unit when measuring and administering Promethazine HCl and Codeine Phosphate Oral Remedy. Advise sufferers that a domestic teaspoon will not be an precise measuring device and this sort of use could lead to overdosage and critical adverse reactions [see Overdosage (10)].

Overdose of codeine in Older people has actually been associated with fatal respiratory melancholy, and the usage of codeine in small children more youthful than 12 decades of age has actually been linked to fatal respiratory depression when utilized as advisable [see Warnings and Precautions (5.

Outcomes around the Gastrointestinal Tract and Other Clean Muscle mass Codeine will cause a reduction in motility linked to an increase in sleek muscle mass tone from the antrum in the tummy and duodenum. Digestion of foodstuff inside the compact intestine is delayed and propulsive contractions are lowered.

Take this medication only as directed by your Promethazine codeine syrup health care provider. Never choose far more of it, never choose it a lot more typically, and don't get it for a longer time than your physician requested. If an excessive amount of this medication is taken for a very long time, it may well become practice-forming and result in psychological or physical dependence.

Explain to your treatment team if your pain won't go away, if it gets even worse, or In case you have new or another kind of discomfort.

Narcotic analgesics or cough suppressants, like codeine, really should not be Employed in asthmatic sufferers (see CONTRAINDICATIONS). Nor should really they be Utilized in acute febrile illness affiliated with productive cough or in Serious respiratory illness where by interference with power to crystal clear the tracheobronchial tree of secretions would have a deleterious effect on the individual's respiratory perform.

If an individual has overdosed and it has significant indicators which include passing out or hassle respiratory, connect with 911. In any other case, contact a poison Command Centre instantly.